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GLP-1RAs have been found to modulate the pathogenesis and progression of migraine by attenuating neuroinflammation and suppressing neuronal hyperactivity [94, 95]

In summary, engineered GLP-1R-targeting nanoplatforms represent a transformative approach in the management of metabolic liver disease, enabling targeted delivery, enhanced pharmacokinetics, and multifunctional therapeutic capabilities that go beyond the limitations of conventional therapies

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doi: 10.1016/S0140-6736(25)02165-8 This article has been republished from the following materials

A very small study of 5 breastfeeding mothers found that tirzepatide levels in breast milk were extremely low or undetectable , but this is very early, preliminary data